Paeonol attenuates inflammation by confining HMGB1 to the nucleus

Volume: 25, Issue: 6, Pages: 2885 - 2899
Published: Feb 3, 2021
Abstract
Inflammation is a biological process that exists in a large number of diseases. If the magnitude or duration of inflammation becomes uncontrolled, inflammation may cause pathological damage to the host. HMGB1 and NF-κB have been shown to play pivotal roles in inflammation-related diseases. New drugs aimed at inhibiting HMGB1 expression have become a key research focus. In the present study, we showed that paeonol (Pae), the main active component...
Paper Details
Title
Paeonol attenuates inflammation by confining HMGB1 to the nucleus
Published Date
Feb 3, 2021
Volume
25
Issue
6
Pages
2885 - 2899
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