Preliminary analysis of the antimicrobial activity of a novel surgical incise drape containing chlorhexidine gluconate against methicillin-resistant Staphylococcus aureus (MRSA) in an in vivo porcine, incisional-wound model

•Adhesive plastic surgical drapes are suggested to reduce the risk of wound sepsis.•Study addresses efficacy of novel chlorhexidine gluconate (CHG)-incised drape in methicillin resistant Staphylococcus aureus porcine wound model.•CHG surgical drape reduced (P < .001) methicillin resistant S aureus contamination of surgical incision site.•Compared to iodophor-impregnated drape CHG drape documented greater efficacy.•Further studies are warranted...