NEDD9 Is a Novel and Modifiable Mediator of Platelet–Endothelial Adhesion in the Pulmonary Circulation

Volume: 203, Issue: 12, Pages: 1533 - 1545
Published: Jun 15, 2021
Abstract
Rationale: Data on the molecular mechanisms that regulate platelet-pulmonary endothelial adhesion under conditions of hypoxia are lacking, but may have important therapeutic implications. Objectives: To identify a hypoxia-sensitive, modifiable mediator of platelet-pulmonary artery endothelial cell adhesion and thrombotic remodeling. Methods: Network medicine was used to profile protein-protein interactions in hypoxia-treated human pulmonary...
Paper Details
Title
NEDD9 Is a Novel and Modifiable Mediator of Platelet–Endothelial Adhesion in the Pulmonary Circulation
Published Date
Jun 15, 2021
Volume
203
Issue
12
Pages
1533 - 1545
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