Microfluidic Preparation of 89Zr-Radiolabelled Proteins by Flow Photochemistry
Abstract
89Zr-radiolabelled proteins functionalised with desferrioxamine B are a cornerstone of diagnostic positron emission tomography. In the clinical setting, 89Zr-labelled proteins are produced manually. Here, we explore the potential of using a microfluidic photochemical flow reactor to prepare 89Zr-radiolabelled proteins. The light-induced functionalisation and 89Zr-radiolabelling of human serum albumin ([89Zr]ZrDFO-PEG3-Et-azepin-HSA) was achieved...
Paper Details
Title
Microfluidic Preparation of 89Zr-Radiolabelled Proteins by Flow Photochemistry
Published Date
Feb 2, 2021
Journal
Volume
26
Issue
3
Pages
764 - 764
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