Chronic Granulomatous Disease

Pages: 289 - 312
Published: Jan 1, 2021
Abstract
Chronic granulomatous disease (CGD) is an inherited primary immunodeficiency due to mutations in any of the critical subunits of the phagocyte NADPH oxidase complex, resulting in impaired oxidase activity of neutrophils, monocytes, and tissue macrophages. It is characterized by increased susceptibility to recurrent and severe infections with a narrow pathognomonic spectrum of bacteria and fungi, granuloma formation, and inflammatory disease,...
Paper Details
Title
Chronic Granulomatous Disease
Published Date
Jan 1, 2021
Journal
Pages
289 - 312
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