Promotion of cancer cell stemness by Ras.

Volume: 49, Issue: 1, Pages: 467 - 476
Published: Feb 26, 2021
Abstract
Cancer stem cells (CSC) may be the most relevant and elusive cancer cell population, as they have the exquisite ability to seed new tumors. It is plausible, that highly mutated cancer genes, such as KRAS, are functionally associated with processes contributing to the emergence of stemness traits. In this review, we will summarize the evidence for a stemness driving activity of oncogenic Ras. This activity appears to differ by Ras isoform, with...
Paper Details
Title
Promotion of cancer cell stemness by Ras.
Published Date
Feb 26, 2021
Volume
49
Issue
1
Pages
467 - 476
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