Ni(ii ), Cu(ii ) and Zn(ii ) complexes with the 1-trifluoroethoxyl-2,9,10-trimethoxy-7-oxoaporphine ligand simultaneously target microtubules and mitochondria for cancer therapy
Abstract
Complexes 1–3 display potent anticancer activity against T-24 cell by disrupting mitochondria and microtubules. Furthermore, complex 1 exhibits almost same tumor growth inhibition activity in T-24 xenograft mouse model as cisplatin and...
Paper Details
Title
Ni(ii ), Cu(ii ) and Zn(ii ) complexes with the 1-trifluoroethoxyl-2,9,10-trimethoxy-7-oxoaporphine ligand simultaneously target microtubules and mitochondria for cancer therapy
Published Date
Jan 1, 2021
Volume
8
Issue
9
Pages
2225 - 2247
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