Unlocking the potential of antibody–drug conjugates for cancer therapy
Abstract
Nine different antibody-drug conjugates (ADCs) are currently approved as cancer treatments, with dozens more in preclinical and clinical development. The primary goal of ADCs is to improve the therapeutic index of antineoplastic agents by restricting their systemic delivery to cells that express the target antigen of interest. Advances in synthetic biochemistry have ushered in a new generation of ADCs, which promise to improve upon the tissue...
Paper Details
Title
Unlocking the potential of antibody–drug conjugates for cancer therapy
Published Date
Feb 8, 2021
Volume
18
Issue
6
Pages
327 - 344
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