False-Negative Results in Lung Cancer Screening—Evidence and Controversies

Identifying false-negative cases is an important quality metric in lung cancer screening, but it has been infrequently and variably reported in previous studies. Although as a proportion of all screening participants, false-negative cases are uncommon, such cases may constitute a substantial proportion of all lung cancers diagnosed (up to 15%) within a screening program.This article reviews the impact and causes of false-negative lung cancer...