The systemic antiangiogenic effect of intravitreal aflibercept injection in a mouse model of retinopathy of prematurity
Abstract
Retinopathy of prematurity (ROP) is a leading cause of childhood blindness and intravitreal anti-vascular endothelial growth factor (VEGF) injection is becoming a first-line choice for treatment of ROP. However, there is a major concern that intravitreally injected anti-VEGF agents could escape from the eye into the systemic circulation and impair systemic development. Moreover, escaped anti-VEGF agents could have an effect on the retina of the...
Paper Details
Title
The systemic antiangiogenic effect of intravitreal aflibercept injection in a mouse model of retinopathy of prematurity
Published Date
Feb 10, 2021
Journal
Volume
35
Issue
3
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