JAK Inhibitors and Modulation of B Cell Immune Responses in Rheumatoid Arthritis
Abstract
Rheumatoid arthritis (RA) is a chronic, systemic immune-mediated inflammatory disease that can lead to joint destruction, functional disability and substantial comorbidity due to the involvement of multiple organs and systems. B cells have several important roles in RA pathogenesis, namely through autoantibody production, antigen presentation, T cell activation, cytokine release and ectopic lymphoid neogenesis. The success of B cell depletion...
Paper Details
Title
JAK Inhibitors and Modulation of B Cell Immune Responses in Rheumatoid Arthritis
Published Date
Feb 5, 2021
Journal
Volume
7
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Notes
History