Modeling, simulation and prediction of protein structures for the design of oncolytic viruses

One of the main problems in the fight against cancer is represented by the immunosuppression it causes. Several research lines have been undertaken to address this issue; one of the most promising is represented by oncolytic viruses. Oncolytic viruses are designed from live attenuated recombinant viruses and are designed to preferentially infect cancer cells, within which they replicate causing their lysis and enhance, through various...