Septins coordinate cell wall integrity and lipid metabolism in a sphingolipid-dependent process
Abstract
Septins colocalize with membrane sterol-rich regions and facilitate recruitment of cell wall synthases during wall remodeling. We show that null mutants missing an Aspergillus nidulans core septin present in hexamers and octamers (ΔaspAcdc11, ΔaspBcdc3 or ΔaspCcdc12) are sensitive to multiple cell wall-disturbing agents that activate the cell wall integrity MAPK pathway. The null mutant missing the octamer-exclusive core septin (ΔaspDcdc10)...
Paper Details
Title
Septins coordinate cell wall integrity and lipid metabolism in a sphingolipid-dependent process
Published Date
Apr 20, 2021
Journal
Volume
135
Issue
5
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