Protective response against Acinetobacter baumannii with ferric iron receptors HemTR-BauA in a murine sepsis model
Abstract
Aim: Iron uptake and metabolism pathways are promising targets in vaccine development as an alternative strategy for antibiotics. Methods & methods: HemTR, a putative heme receptor of Acinetobacter baumannii, was expressed and its protectivity against A. baumannii was determined singly or in combination with the siderophore receptor, BauA, in mice. Results: High level of IgG was elicited. There was a delay in mice mortality with reduced...
Paper Details
Title
Protective response against Acinetobacter baumannii with ferric iron receptors HemTR-BauA in a murine sepsis model
Published Date
Feb 1, 2021
Journal
Volume
16
Issue
3
Pages
159 - 173
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