Diabetes Mellitus, Glycemic Traits, and Cerebrovascular Disease
Abstract
We employed Mendelian randomization to explore the effects of genetic predisposition to type 2 diabetes (T2D), hyperglycemia, insulin resistance, and pancreatic β-cell dysfunction on risk of stroke subtypes and related cerebrovascular phenotypes.We selected instruments for genetic predisposition to T2D (74,124 cases, 824,006 controls), HbA1c levels (n = 421,923), fasting glucose levels (n = 133,010), insulin resistance (n = 108,557), and β-cell...
Paper Details
Title
Diabetes Mellitus, Glycemic Traits, and Cerebrovascular Disease
Published Date
Mar 30, 2021
Journal
Volume
96
Issue
13
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