Nicotinamide Improves Cognitive Function in Mice With Chronic Cerebral Hypoperfusion
Abstract
Normal brain function requires steady blood supply to maintain stable energy state. When blood supply to the brain becomes suboptimal for a long period of time, chronic cerebral hypoperfusion (CCH) and a variety of brain changes may occur. CCH causes white matter injury and cognitive impairment. The present study investigated the effect of nicotinamide (NAM) on CCH-induced cognitive impairment and white matter damage in mice. Male C57Bl/6J mice...
Paper Details
Title
Nicotinamide Improves Cognitive Function in Mice With Chronic Cerebral Hypoperfusion
Published Date
Jan 25, 2021
Journal
Volume
12
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