Resistance to Antiandrogens in Prostate Cancer: Is It Inevitable, Intrinsic or Induced?
Abstract
Increasingly sophisticated therapies for chemical castration dominate first-line treatments for locally advanced prostate cancer. However, androgen deprivation therapy (ADT) offers little prospect of a cure, as resistant tumors emerge rather rapidly, normally within 30 months. Cells have multiple mechanisms of resistance to even the most sophisticated drug regimes, and both tumor cell heterogeneity in prostate cancer and the multiple salvage...
Paper Details
Title
Resistance to Antiandrogens in Prostate Cancer: Is It Inevitable, Intrinsic or Induced?
Published Date
Jan 17, 2021
Journal
Volume
13
Issue
2
Pages
327 - 327
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