Microsatellite instability/mismatch repair deficiency in pancreatic cancers: the same or different?

Pancreatic cancer frustrates patients, clinicians and scientists. Five-year overall survival is the worst among common cancers, stubbornly remaining below 10%.1 Despite large international efforts offering unprecedented insights into pancreatic cancer biology in the last 10 years,2 patients with pancreatic cancer have not experienced the exciting translational advances in screening and treatment recently observed in other cancers, with few...