Characterization of human T cell receptor repertoire data in eight thymus samples and four related blood samples
Abstract
T cell receptor (TCR) is a heterodimer consisting of TCRα and TCRβ chains that are generated by somatic recombination of multiple gene segments. Nascent TCR repertoire undergoes thymic selections where non-functional and potentially autoreactive receptors are removed. During the last years, the development of high-throughput sequencing technology has allowed a large scale assessment of TCR repertoire and multiple analysis tools are now also...
Paper Details
Title
Characterization of human T cell receptor repertoire data in eight thymus samples and four related blood samples
Published Date
Apr 1, 2021
Journal
Volume
35
Pages
106751 - 106751
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