Contact-independent killing mediated by a T6SS effector with intrinsic cell-entry properties
Abstract
Bacterial type VI secretion systems (T6SSs) inject toxic effectors into adjacent eukaryotic and prokaryotic cells. It is generally thought that this process requires physical contact between the two cells. Here, we provide evidence of contact-independent killing by a T6SS-secreted effector. We show that the pathogen Yersinia pseudotuberculosis uses a T6SS (T6SS-3) to secrete a nuclease effector that kills other bacteria in vitro and facilitates...
Paper Details
Title
Contact-independent killing mediated by a T6SS effector with intrinsic cell-entry properties
Published Date
Jan 18, 2021
Journal
Volume
12
Issue
1
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