Dose-dependent emergence of acute and recurrent corneal lesions in sulfur mustard-exposed rabbit eyes
Abstract
Sulfur mustard (SM) is a lipid soluble alkylating agent that causes genotoxic injury. The eye is highly sensitive to SM toxicity and exposures exceeding 400 mg min/m3 can elicit irreversible corneal pathophysiologies. Development of medical countermeasures for ocular SM exposure has been hindered by a limited understanding of dose-dependent effects of SM on corneal injury. Here, clinical, histological and ultrastructural analyses were used to...
Paper Details
Title
Dose-dependent emergence of acute and recurrent corneal lesions in sulfur mustard-exposed rabbit eyes
Published Date
May 1, 2021
Journal
Volume
341
Pages
33 - 42
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