Metabolomic analysis of plasma from normal‐weight adults with hypo‐HDL cholesterolemia by UPLC–QTOF MS

High‐density lipoprotein cholesterol (HDL‐C) is negatively correlated with atherosclerotic cardiovascular disease. The prevalence of hypo‐HDL cholesterolemia is as high as 33.9%. The plasma metabolomic differences between hypo‐HDL cholesterolemia populations and normal controls were investigated using ultra‐high‐performance liquid chromatography–quadrupole time‐of‐flight mass spectrometry. Participants with hypo‐HDL cholesterolemia and normal...