Sleep and the ovarian axis

Multiple interactions between sleep and the ovarian axis are operative in physiological and pathological conditions. Both estradiol and progesterone contribute to the regulation of specific sleep stages, which in turn contribute to the regulation of pulsatile secretion of gonadotropins. Sleep troubles, in particular sleep deprivation, may be associated with menstrual cycle irregularity, anovulation, and miscarriage. In addition, insufficient...