Semi-interpenetrating polymeric networks based on poly(dimethylsiloxane)-chitosan-poly(vinyl alcohol) crosslinked with genipin with possible use in biomedical applications

We demonstrate that semi-interpenetrating polymeric networks are obtained by blending synthetic and natural polymers such as poly(dimethylsiloxane) (PDMS), poly(vinyl alcohol) (PVA), and chitosan (CS) crosslinked with glutaraldehyde (GA) or genipin (GEN). In membrane shape, these polymeric networks combine the elasticity of PDMS, the swelling capability of PVA, and the excellent cellular adhesion of CS successfully. Moreover, with the...