Anthraquinones inhibit cytochromes P450 enzyme activity in silico and in vitro
Abstract
Anthraquinones exhibit various pharmacological activities (e.g., antioxidant and laxative) and are commonly found in consumer products including foods, dietary supplements, drugs, and traditional medicines. Despite their widespread use, there are limited data available on their toxicokinetic properties. Cytochrome P450 enzymes (CYPs) in the liver play major roles in metabolizing exogenous chemicals (e.g., pharmaceuticals, food ingredients, and...
Paper Details
Title
Anthraquinones inhibit cytochromes P450 enzyme activity in silico and in vitro
Published Date
Jan 12, 2021
Volume
41
Issue
9
Pages
1438 - 1445
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