Arginine methylation: the promise of a ‘silver bullet’ for brain tumours?
Abstract
Despite intense research efforts, our pharmaceutical repertoire against high-grade brain tumours has not been able to increase patient survival for a decade and life expectancy remains at less than 16 months after diagnosis, on average. Inhibitors of protein arginine methyltransferases (PRMTs) have been developed and investigated over the past 15 years and have now entered oncology clinical trials, including for brain tumours. This review...
Paper Details
Title
Arginine methylation: the promise of a ‘silver bullet’ for brain tumours?
Published Date
Jan 6, 2021
Journal
Volume
53
Issue
4
Pages
489 - 506
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