WWC Proteins: Important Regulators of Hippo Signaling in Cancer

Volume: 13, Issue: 2, Pages: 306 - 306
Published: Jan 15, 2021
Abstract
The Hippo signaling pathway is known to regulate cell differentiation, proliferation and apoptosis. Whereas activation of the Hippo signaling pathway leads to phosphorylation and cytoplasmic retention of the transcriptional coactivator YAP, decreased Hippo signaling results in nuclear import of YAP and subsequent transcription of pro-proliferative genes. Hence, a dynamic and precise regulation of the Hippo signaling pathway is crucial for organ...
Paper Details
Title
WWC Proteins: Important Regulators of Hippo Signaling in Cancer
Published Date
Jan 15, 2021
Journal
Volume
13
Issue
2
Pages
306 - 306
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