Viewpoint ;European COVID-19 exit strategy for people with severe mental disorders: too little, but not yet too late

Published on Jan 22, 2021in Brain Behavior and Immunity6.633
· DOI :10.1016/J.BBI.2021.01.008
Livia De Picker8
Estimated H-index: 8
(University of Antwerp),
L. De Picker1
Estimated H-index: 1
(University of Antwerp)
+ 11 AuthorsEcnp Immuno-NeuroPsychiatry Twg1
Estimated H-index: 1
#1Nicola Warren (UQ: University of Queensland)H-Index: 8
#2Steve Kisely (Dal: Dalhousie University)H-Index: 42
Last. Dan Siskind (UQ: University of Queensland)H-Index: 31
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eople with serious mental illness (SMI) are at increased risk of being infected by coronavirus disease 2019 (COVID-19) and have higher subsequent rates of hospitalization, morbidity, and mortality.1,2 Factors that contribute to worse outcomes include concomitant medications, poorer premorbid general health, physical comorbidity, reduced access to medical care, and environmental and lifestyle factors such as lower socioeconomic status, overcrowding, smoking, or obesity. In light of these vulnerab...
10 CitationsSource
#1Katlyn Nemani (NYU: New York University)H-Index: 3
#2Chenxiang Li (NYU: New York University)H-Index: 3
Last. Donald C. Goff (Nathan Kline Institute for Psychiatric Research)H-Index: 99
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Importance To date, the association of psychiatric diagnoses with mortality in patients infected with coronavirus disease 2019 (COVID-19) has not been evaluated. Objective To assess whether a diagnosis of a schizophrenia spectrum disorder, mood disorder, or anxiety disorder is associated with mortality in patients with COVID-19. Design, Setting, and Participants This retrospective cohort study assessed 7348 consecutive adult patients for 45 days following laboratory-confirmed COVID-19 between Ma...
44 CitationsSource
#1QuanQiu Wang (Case Western Reserve University)H-Index: 16
#2Rong Xu (Case Western Reserve University)H-Index: 35
Last. Nora D. VolkowH-Index: 183
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Concerns have been expressed that persons with a pre-existing mental disorder may represent a population at increased risk for COVID-19 infection and with a higher likelihood of adverse outcomes of the infection, but there is no systematic research evidence in this respect. This study assessed the impact of a recent (within past year) diagnosis of a mental disorder - including attention-deficit/hyperactivity disorder (ADHD), bipolar disorder, depression and schizophrenia - on the risk for COVID-...
110 CitationsSource
#1Maxime TaquetH-Index: 16
#2Sierra LucianoH-Index: 7
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#1Seung Won Lee (Sejong University)H-Index: 14
#2Jee Myung Yang (UOU: University of Ulsan)H-Index: 12
Last. Dong Keon YonH-Index: 10
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Summary Background Evidence for the associations between mental illness and the likelihood of a positive severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) test result and the clinical outcomes of COVID-19 is scarce. We aimed to investigate these associations with data from a national register in South Korea. Methods A nationwide cohort study with propensity score matching was done in South Korea using data collected from the Health Insurance Review and Assessment Service of Korea. We ...
50 CitationsSource
#1Rebecca De Lorenzo (UniSR: Vita-Salute San Raffaele University)H-Index: 8
#2Caterina Conte (UniSR: Vita-Salute San Raffaele University)H-Index: 22
Last. Patrizia Rovere-Querini (UniSR: Vita-Salute San Raffaele University)H-Index: 66
view all 21 authors...
Data on residual clinical damage after Coronavirus disease-2019 (COVID-19) are lacking. The aims of this study were to investigate whether COVID-19 leaves behind residual dysfunction, and identify patients who might benefit from post-discharge monitoring. All patients aged ≥18 years admitted to the Emergency Department (ED) for COVID-19, and evaluated at post-discharge follow-up between 7 April and 7 May, 2020, were enrolled. Primary outcome was need of follow-up, defined as the presence at foll...
24 CitationsSource
#1Luming Li (Yale University)H-Index: 7
#2Fangyong Li (Yale University)H-Index: 1
Last. John H. Krystal (Yale University)H-Index: 143
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This cohort study evaluates the association between prior psychiatric diagnosis and mortality among patients hospitalized with coronavirus disease 2019 (COVID-19).
35 CitationsSource
#1Maxime Taquet (Oxford Health NHS Foundation Trust)H-Index: 1
#1Maxime Taquet (Oxford Health NHS Foundation Trust)H-Index: 16
Last. Paul Harrison (University of Oxford)H-Index: 162
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Background: Adverse mental health consequences of COVID-19, including anxiety and depression, have been widely predicted but not yet accurately measured. There are a range of physical health risk factors for COVID-19, but it is not known if there are also psychiatric risk factors. Methods: We addressed both questions using cohort studies derived from an electronic health records (EHR) network of 69 million patients including over 62,000 cases of COVID-19. Propensity score matching was used to co...
15 CitationsSource
#2Rebecca De Lorenzo (UniSR: Vita-Salute San Raffaele University)H-Index: 8
Last. Francesco Benedetti (UniSR: Vita-Salute San Raffaele University)H-Index: 68
view all 11 authors...
Abstract Infection-triggered perturbation of the immune system could induce psychopathology, and psychiatric sequelae were observed after previous coronavirus outbreaks. The spreading of the Severe Acute Respiratory Syndrome Coronavirus (COVID-19) pandemic could be associated with psychiatric implications. We investigated the psychopathological impact of COVID-19 in survivors, also considering the effect of clinical and inflammatory predictors. We screened for psychiatric symptoms 402 adults sur...
203 CitationsSource
#1Wonjun Ji (UOU: University of Ulsan)H-Index: 12
#2Kyungmin Huh (SMC: Samsung Medical Center)H-Index: 14
Last. Jaehun Jung (Gachon University)H-Index: 11
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BACKGROUND: The coronavirus disease 2019 (COVID-19) pandemic is an emerging threat worldwide. It remains unclear how comorbidities affect the risk of infection and severity of COVID-19. METHODS: This is a nationwide retrospective case-control study of 219,961 individuals, aged 18 years or older, whose medical costs for COVID-19 testing were claimed until May 15, 2020. COVID-19 diagnosis and infection severity were identified from reimbursement data using diagnosis codes and on the basis of respi...
59 CitationsSource
Cited By7
#1L. De Picker (University of Antwerp)H-Index: 1
#1Livia De Picker (University of Antwerp)H-Index: 8
#1Hans Rittmannsberger (Steyr Mannlicher)H-Index: 5
#2Martin Barth (Steyr Mannlicher)
Last. Kurosch Yazdi (Johannes Kepler University of Linz)
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Das Virus SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus Type 2) und null null null null null null null null null null null null null null null null null null null die von ihm ausgeloste Erkrankung COVID-19 (Coronavirus Disease 2019) null null null null null null null null null null null null null null null null null null null konnen zahlreiche Organsysteme betreffen. In vorliegender Arbeit bieten null null null null null null null null null null null null null null null null null nul...
#1Benedetta Vai (UniSR: Vita-Salute San Raffaele University)H-Index: 17
#2Mario Gennaro Mazza (UniSR: Vita-Salute San Raffaele University)H-Index: 5
Last. Livia De Picker (University of Antwerp)H-Index: 8
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Background: Mental disorders may represent a risk factor for severe COVID-19. This study evaluated the risk of COVID-19 mortality, hospitalization, and intensive care unit (ICU) admission in patients with pre-existing mental disorders or exposure to psychopharmacological treatments. Methods: In this PRISMA-compliant systematic review and meta-analysis (PROSPERO-CRD42021233984), we searched Web of Science, PsycINFO, Cochrane, PubMed, and Ovid/PsycINFO databases through March 5, 2021 for studies r...
4 CitationsSource
#1Natascia Brondino (UNIPV: University of Pavia)H-Index: 20
#2Federico Bertoglio (Braunschweig University of Technology)H-Index: 12
Last. Monica Caviglia (UNIPV: University of Pavia)H-Index: 1
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Background: Several neurobiological mechanisms have been proposed to support the hypothesis of a higher COVID-19 risk in individuals with autism spectrum disorder (ASD). However, no real-world data are available on this population. Methods: We compared the period prevalence (March-May 2020) and symptom presentation of COVID-19 infections between a sample of individuals with severe ASD (n = 36) and the staff personnel (n = 35) of two specialized centers. Anti-SARS-Cov-2 antibody positivity was us...
#1Paolo Fusar-PoliH-Index: 96
#2Sameer JauharH-Index: 22
Last. P. McGuire ('KCL': King's College London)H-Index: 1
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#1Livia De PickerH-Index: 8
#2Marisa Casanova Dias (Centre for Mental Health)H-Index: 1
Last. Marion LeboyerH-Index: 120
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