Development and structural basis of a two-MAb cocktail for treating SARS-CoV-2 infections
Abstract
The ongoing pandemic of coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Neutralizing antibodies against SARS-CoV-2 are an option for drug development for treating COVID-19. Here, we report the identification and characterization of two groups of mouse neutralizing monoclonal antibodies (MAbs) targeting the receptor-binding domain (RBD) on the SARS-CoV-2 spike (S) protein. MAbs 2H2...
Paper Details
Title
Development and structural basis of a two-MAb cocktail for treating SARS-CoV-2 infections
Published Date
Jan 11, 2021
Journal
Volume
12
Issue
1
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