Recent advances in PTEN signalling axes in cancer
Abstract
In over two decades since the discovery of phosphatase and tensin homologue deleted on chromosome 10 (PTEN), nearly 18,000 publications have attempted to elucidate its functions and roles in normal physiology and disease. The frequent disruption of PTEN in cancer cells was a strong indication that it had critical roles in tumour suppression. Germline PTEN mutations have been identified in patients with heterogeneous tumour syndromic diseases,...
Paper Details
Title
Recent advances in PTEN signalling axes in cancer
Published Date
Dec 23, 2020
Journal
Volume
9
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History