Hair cell uptake of gentamicin in the developing mouse utricle
Abstract
Intratympanic injection of gentamicin has proven to be an effective therapy for intractable vestibular dysfunction. However, most studies to date have focused on the cochlea, so little is known about the distribution and uptake of gentamicin by the counterpart of the auditory system, specifically vestibular hair cells (HCs). Here, with a combination of in vivo and in vitro approaches, we used a gentamicin-Texas Red (GTTR) conjugate to...
Paper Details
Title
Hair cell uptake of gentamicin in the developing mouse utricle
Published Date
Dec 23, 2020
Volume
236
Issue
7
Pages
5235 - 5252
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