MicroRNA‑140‑5p regulates the proliferation, apoptosis and inflammation of RA FLSs by repressing STAT3

Ectopic expression of microRNA (miRNA) in rheumatoid arthritis (RA) fibroblast‑like synoviocyte (RA FLS) is associated with the development of rheumatoid arthritis. The present study aimed to evaluate the effects of miRNA‑140‑5p (miR‑140) on the properties of RA FLSs. It was found that miR‑140 expression was decreased in 33 RA patients and extracted RA FLS samples, when compared to the corresponding healthy controls. Abnormally increased miR‑140...