Revisiting heart failure assessment based on objective measures in NYHA functional classes I and II

New York Heart Association (NYHA) functional class plays a central role in heart failure (HF) assessment but might be unreliable in mild presentations. We compared objective measures of HF functional evaluation between patients classified as NYHA I and II in the Rede Brasileira de Estudos em Insuficiência Cardíaca (ReBIC)-1 Trial.The ReBIC-1 Trial included outpatients with stable HF with reduced ejection fraction. All patients had simultaneous...