HBV RNA, Hepatitis B Core-Related Antigen, and Quantitative Hepatitis B Surface Antigen Biomarkers to Predict Outcome of Antiviral Therapy

We read with interest the article by Sonneveld and colleagues,1Sonneveld M.J. et al.Clin Gastroenterol Hepatol. 2020; ([Epub ahead of print])Google Scholar who have investigated the relationship between end-of-treatment levels of hepatitis B core related antigen (HBcrAg) and hepatitis B surface antigen (HBsAg) and outcome after therapy cessation. In their multicenter study, the authors found that lower levels of HBcrAg and HBsAg were associated...