Scaffold-based 3D cellular models mimicking the heterogeneity of osteosarcoma stem cell niche
Abstract
The failure of the osteosarcoma conventional therapies leads to the growing need for novel therapeutic strategies. The lack of specificity for the Cancer Stem Cells (CSCs) population has been recently identified as the main limitation in the current therapies. Moreover, the traditional two-dimensional (2D) in vitro models, employed in the drug testing and screening as well as in the study of cell and molecular biology, are affected by a poor in...
Paper Details
Title
Scaffold-based 3D cellular models mimicking the heterogeneity of osteosarcoma stem cell niche
Published Date
Dec 18, 2020
Journal
Volume
10
Issue
1
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