Dipeptidyl peptidase 4 inhibitors attenuate cardiac ischaemia–reperfusion injury in rats with diabetes mellitus type 2

Volume: 48, Issue: 4, Pages: 575 - 584
Published: Dec 22, 2020
Abstract
The aim of our study was to assess and compare the effects of dipeptidyl peptidase 4 (DPP4) inhibitors, saxagliptin and sitagliptin, on metabolic control of disease and cardiac function in rats with diabetes mellitus type 2 (T2DM). This research would provide novel understanding into the potentially protective effects of DPP4 inhibitors in helping salvage of the heart exposed to ischaemia–reperfusion (I–R) injury. Forty-eight Wistar albino rats...
Paper Details
Title
Dipeptidyl peptidase 4 inhibitors attenuate cardiac ischaemia–reperfusion injury in rats with diabetes mellitus type 2
Published Date
Dec 22, 2020
Volume
48
Issue
4
Pages
575 - 584
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