Indirect Suppression of Pulsatile LH Secretion by CRH Neurons in the Female Mouse
Abstract
Acute stress is a potent suppressor of pulsatile luteinizing hormone (LH) secretion, but the mechanisms through which corticotrophin-releasing hormone (CRH) neurons inhibit gonadotropin-releasing hormone (GnRH) release remain unclear. The activation of paraventricular nucleus (PVN) CRH neurons with Cre-dependent hM3Dq in Crh-Cre female mice resulted in the robust suppression of pulsatile LH secretion. Channelrhodopsin (ChR2)-assisted circuit...
Paper Details
Title
Indirect Suppression of Pulsatile LH Secretion by CRH Neurons in the Female Mouse
Published Date
Dec 26, 2020
Journal
Volume
162
Issue
3
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