Polyzwitterion-crosslinked hybrid tissue with antithrombogenicity, endothelialization, anticalcification properties

Although transcatheter aortic valve implantation (TAVI) has been proven with excellent effectiveness and safety, the subclinical leaflet thrombosis (SLT) and structural valve deterioration (SVD) are two main factors threatening the service lifespan of the transcatheter aortic valve (TAV) because the glutaraldehyde (Glut) crosslinked tissue as leaflet material for the current clinically used TAV has high calcification propensity and...