(S)-(-)-N-[2-(3-Hydroxy-2-oxo-2,3-dihydro-1H-indol-3-yl)-ethyl]-acetamide inhibits melanoma cell growth through inducing apoptosis and autophagy.
Abstract
Melanoma is the most lethal form of skin cancer with the incidence drastically increasing over the past several decades. (S)-(-)-N-[2-(3-Hydroxy-2-oxo-2,3-dihydro-1H-indol-3-yl)-ethyl]-acetamide (SA) was a new compound isolated from the leaves of Selaginella pulvinata, with potent activities to inhibit the proliferation of SK-mel-110 cells. This study was to further investigate effects of SA against melanoma and explore its underlying...
Paper Details
Title
(S)-(-)-N-[2-(3-Hydroxy-2-oxo-2,3-dihydro-1H-indol-3-yl)-ethyl]-acetamide inhibits melanoma cell growth through inducing apoptosis and autophagy.
Published Date
Dec 1, 2021
Volume
40
Issue
4
Pages
293 - 299
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