A selection pressure landscape for 870 human polygenic traits

Volume: 5, Issue: 12, Pages: 1731 - 1743
Published: Nov 15, 2021
Abstract
Characterizing the natural selection of complex traits is important for understanding human evolution and both biological and pathological mechanisms. We leveraged genome-wide summary statistics for 870 polygenic traits and attempted to quantify signals of selection on traits of different forms in European ancestry across four periods in human history and evolution. We found that 88% of these traits underwent polygenic change in the past...
Paper Details
Title
A selection pressure landscape for 870 human polygenic traits
Published Date
Nov 15, 2021
Volume
5
Issue
12
Pages
1731 - 1743
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