Organelle-specific mechanisms of drug-induced autophagy-dependent cell death
Abstract
The conserved catabolic process of autophagy is an important control mechanism that degrades cellular organelles, debris and pathogens in autolysosomes. Although autophagy primarily protects against cellular insults, nutrient starvation or oxidative stress, hyper-activation of autophagy is also believed to cause autophagy-dependent cell death (ADCD). ADCD is a caspase-independent form of programmed cell death (PCD), characterized by an...
Paper Details
Title
Organelle-specific mechanisms of drug-induced autophagy-dependent cell death
Published Date
Jun 1, 2021
Journal
Volume
100-101
Pages
54 - 64
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