Vitamin D deficiency worsens maternal diabetes induced neurodevelopmental disorder by potentiating hyperglycemia‐mediated epigenetic changes

Volume: 1491, Issue: 1, Pages: 74 - 88
Published: Dec 10, 2020
Abstract
Many studies have shown that vitamin D (VD) deficiency may be a risk factor for neurodevelopmental disorders, such as autism spectrum disorders (ASDs) and schizophrenia, although causative mechanisms remain unknown. In this study, we investigated the potential role and effect of VD on maternal diabetes induced autism‐related phenotypes. The in vitro study found that enhancing genomic VD signaling by overexpressing the VD receptor (VDR) in human...
Paper Details
Title
Vitamin D deficiency worsens maternal diabetes induced neurodevelopmental disorder by potentiating hyperglycemia‐mediated epigenetic changes
Published Date
Dec 10, 2020
Volume
1491
Issue
1
Pages
74 - 88
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