Role of autophagy in intervertebral disc and cartilage function: implications in health and disease

Volume: 100-101, Pages: 207 - 220
Published: Jun 1, 2021
Abstract
The intervertebral disc and cartilage are specialized, extracellular matrix-rich tissues critical for absorbing mechanical loads, providing flexibility to the joints, and longitudinal growth in the case of growth plate cartilage. Specialized niche conditions in these tissues, such as hypoxia, are critical in regulating cellular activities including autophagy, a lysosomal degradation pathway that promotes cell survival. Mounting evidence suggests...
Paper Details
Title
Role of autophagy in intervertebral disc and cartilage function: implications in health and disease
Published Date
Jun 1, 2021
Volume
100-101
Pages
207 - 220
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