444 Genomic and functional characterisation of intra-tumoural heterogeneity in high grade serous ovarian cancer

Published: Dec 1, 2020
Abstract

Introduction/Background

High-grade serous ovarian cancer (HGSOC) is characterised by high degrees of genomic instability and heterogeneity, with most patients eventually acquiring resistance to platinum-based chemotherapy. Matching the best treatment options to patients remains problematic due to diverse platinum resistance mechanisms and limited effective predictive biomarkers. This study aims to understand the extent of intra-tumoural...
Paper Details
Title
444 Genomic and functional characterisation of intra-tumoural heterogeneity in high grade serous ovarian cancer
Published Date
Dec 1, 2020
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