Noninvasive characterization of Alzheimer’s disease by circulating, cell-free messenger RNA next-generation sequencing
Abstract
The lack of accessible noninvasive tools to examine the molecular alterations occurring in the brain limits our understanding of the causes and progression of Alzheimer's disease (AD), as well as the identification of effective therapeutic strategies. Here, we conducted a comprehensive profiling of circulating, cell-free messenger RNA (cf-mRNA) in plasma of 126 patients with AD and 116 healthy controls of similar age. We identified 2591...
Paper Details
Title
Noninvasive characterization of Alzheimer’s disease by circulating, cell-free messenger RNA next-generation sequencing
Published Date
Dec 11, 2020
Journal
Volume
6
Issue
50
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