Fructan‐sensitive children with irritable bowel syndrome have distinct gut microbiome signatures

Dietary fructans may worsen gastrointestinal symptoms in children with irritable bowel syndrome (IBS).To determine whether gut microbiome composition and function are associated with childhood IBS fructan-induced symptoms.Faecal samples were collected from 38 children aged 7-17 years with paediatric Rome III IBS, who previously completied a double-blind, randomised, placebo-controlled crossover (fructan vs maltodextrin) trial. Fructan...