The composition differences between small black beans and big black beans from different habitats and its effects on the processing of Polygonum multiflorum

Introduction The roots of Polygonum multiflorum (PM) serve as a classical traditional Chinese medicine (TCM), which has multiple biological activities. However, many cases of hepatotoxicity in PM have been reported in recent years. Processing PM with black beans decoction is one of the typical processing methods to reduce the hepatotoxicity of PM since ancient times. Objectives To find potential effective constituents, as well as the optimal...