SIRT4 expression in laryngeal squamous cell carcinoma.

SIRT4 has been reported to be abnormally expressed in many malignant tumor tissues, but data in laryngeal squamous cell carcinoma (LSCC) is lacking. In the present study, we detected the expression of SIRT4 in 168 pairs of LSCC tissues and adjacent normal tissues using RT-qPCR, immunoblotting and immunohistochemical staining, and analyzed its clinical implication. We found that SIRT4 expression was low in LSCC tissues, and was significantly...