Echocardiography-Guided Risk Stratification for Long QT Syndrome

The ability to identify those patients at the highest phenotypic risk for long QT syndrome (LQTS)–associated life-threatening cardiac events remains suboptimal. This study sought to validate the association between electromechanical window (EMW) negativity, as derived from echocardiography, and symptomatic versus asymptomatic status in patients with LQTS. We analyzed a cohort of 651 patients with LQTS (age 26 ± 17 years; 60% females; 158...