Relentless Placoid Chorioretinitis in a Young Man

Published on Dec 15, 2020in Journal of The Korean Ophthalmological Society
· DOI :10.3341/JKOS.2020.61.12.1542
Tae Hoon Kim38
Estimated H-index: 38
Chang Zoo Kim1
Estimated H-index: 1
+ 2 AuthorsGwang Myeong Noh2
Estimated H-index: 2
#1Shotaro Asano (UTokyo: University of Tokyo)H-Index: 5
#2Rie Tanaka (UTokyo: University of Tokyo)H-Index: 9
Last. Toshikatsu KaburakiH-Index: 19
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Background: Adalimumab, a human anti-tumor necrosis factor-ɑ monoclonal antibody, was recently reported to be effective in lowering the risk of recurrence of noninfectious uveitis. This is the first case series of adalimumab administrations for relentless placoid chorioretinitis (RPC) patients. Case Presentation: We report 2 cases of RPC where successful treatments were achieved with adalimumab. A 34-year-old woman developed conjunctival hyperemia, mild iridocyclitis, and multiple atrophic retin...
2 CitationsSource
#1Takehiko Uraki (Hokkaido University)H-Index: 2
#2Kenichi Namba (Hokkaido University)H-Index: 28
Last. Susumu Ishida (Hokkaido University)H-Index: 52
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Abstract Purpose Relentless placoid chorioretinitis (RPC) is a new disease concept that was proposed by Jones et al. in 2000. Some cases of RPC have been reported; however, a treatment strategy has not yet been established. We report herein four cases of patients diagnosed with RPC. Observations We experienced four cases of RPC in patients aged 24–51 years. All patients exhibited retinal lesions similar to that seen in acute posterior multifocal placoid pigment epitheliopathy or serpiginous chor...
2 CitationsSource
#1D. B. Roth (UMDNJ: University of Medicine and Dentistry of New Jersey)H-Index: 5
Last. Howard F FineH-Index: 21
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PURPOSE: To report a case of relentless placoid chorioretinitis (ampiginous choroiditis) treated with intravitreal triamcinolone acetonide (IVTA). METHODS: Interventional case report. RESULTS: A 34-year-old pregnant woman with a history of poor visual acuity in her left eye, secondary to an undetermined cause, developed an acute painless central scotoma and blurred vision in the right eye. The examination revealed decreased visual acuity, active inflammatory placoid choroidal lesions in the post...
4 CitationsSource
Background The purpose of this study is to evaluate the retinal and choroidal thickness of the macular region in patients with unilateral relentless placoid chorioretinitis (RPC) and macular involvement. Patients diagnosed with RPC affecting only one eye underwent a comprehensive ophthalmologic examination including best-corrected visual acuity (BCVA), axial length (AL) measurement, slit-lamp examination, and color fundus and autofluorescence photography. The macular region was scanned by swept-...
5 CitationsSource
12 CitationsSource
#1Steven YehH-Index: 32
#2Julie C. LewH-Index: 6
Last. Robert B. NussenblattH-Index: 99
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10 CitationsSource
#1Biswas Jyotirmay (SN: Sankara Nethralaya)H-Index: 2
#2Shafiq S. Jafferji (SN: Sankara Nethralaya)H-Index: 1
Last. Badami KalpanaH-Index: 1
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The purpose of this study was to report the clinical profile and management of patients with serpiginous choroiditis in a tertiary care referral center in India. In a retrospective cohort study, 107 eyes of 70 patients with serpiginous choroiditis seen between January 1995 and December 2002 were analyzed. Systemic steroids and immunosuppressives were the mainstay of therapy. Antituberculous and antiviral drugs were used in selected cases. There was male preponderance (7:3). Age at presentation r...
51 CitationsSource
#1Tadashi Orihara (Kyorin University)H-Index: 4
#2Toshiko Wakabayashi (Kyorin University)H-Index: 7
Last. Tetsuo Hida (Kyorin University)H-Index: 27
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Jones and colleagues described a clinical entity they called relentless placoid chorioretinitis, characterized by features similar to both acute posterior multifocal placoid pigment epitheliopathy (APMPPE) and serpiginouschoroiditis, but with atypical features for either of these diseases. 1 Here we describe a young Japanese man with what we believe fits their description of relentless placoid chorioretinitis.
5 CitationsSource
#1B. Eric Jones (U of C: University of Chicago)H-Index: 1
#2Lee M. Jampol (U of C: University of Chicago)H-Index: 75
Last. David F. WilliamsH-Index: 20
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Objective: To characterize an unusual clinical entity resembling acute posterior multifocal placoid pigment epitheliopathy (APMPPE) and serpiginous choroiditis but with an atypical clinical course. Patients: We describe 6 patients, aged 17 through 51 years, exhibiting this unusual entity who were seen at 6 different centers from 1984 to 1997. Results: The acute retinal lesions in this series were similar to those of APMPPE or serpiginous choroiditis, both clinically and on fluorescein and indocy...
89 Citations
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